Antibody Diversification and DNA Deaminases in Immunity and Cancer

20 years since the discovery of Activation-Induced Cytidine Deaminase


This meeting commemorates the 20th anniversary of the discovery of AID (Activation-Induce Cytidine Deaminase), and its role in antibody diversification.

 

In addition to AID biology, this meeting will be dedicated to other processes that are closely related or have directly derived from this discovery. These include the role of AID in the germinal center reaction, DNA repair during antibody diversification, the genomic landscape during antibody diversification, the role of the AID paralogue enzymes APOBEC in innate immunity, and the development and use of therapeutic antibodies in infectious disease and cancer.

 

Organizers

 

Javier Di Noia

(Institut de Recherches Cliniques de Montréal & Department of Medicine, University of Montreal)

Marc-André Langlois

(Department of Biochemistry, Microbiology and Immunology, University of Ottawa)

Rossanna Pezo

(Sunnybrook Research Institute)

Alberto Martin

(Department of Immunology, University of Toronto)

 

 

Keynote speakers

 

Tasuku Honjo

(Kyoto University, Japan; Nobel Laureate in physiology and medicine 2018)

 

Frederick Alt

(Harvard University, USA; member of the National Academy of Sciences USA)

 

Michel Nussenzweig

(Rockefeller University, USA; member of the National Academy of Sciences USA)

 

Plenary session speakers

    

Uttiya Basu (USA)

Nasim Begum (Japan)

Ashok Bhagwat (USA)

Jayanta Chaudhuri (USA)

Linda Chelico (Canada)

Michel Cogné (France)

Silvo Conticello (Italy)

Michela Di Virgilio (Germany)

Javier Di Noia (Canada)

Patricia Gearhart (USA)

Myron Goodman (USA)

Reuben Harris (USA)

Chris Jolly (Australia)

Jean Philippe Julien (Canada)

Garnett Kelsoe (USA)

Amy Kenter (USA)

Maki Kobayashi (Japan)

Marc-André Langlois (Canada)

Mani Larijani (Canada)

Michael Malim (England)

Alberto Martin (Canada)

Kevin McBride (USA)

Feilong Meng (China)

Alexandre Orthwein (Canada)

Qiang Pan Hammarstrom (Sweden)

Nina Papavasiliou (Germany)

Rushad Pavri (Austria)

Almudena Ramiro (Spain)

Anjana Rao (USA)
Bernardo Reina San Martin (France)
Sergio Roa (Spain)
Matthew Scharff (USA)
David Schatz (USA)
Kefei Yu (USA)

 

The organizers would like to thank the institutions and companies that sponsor this event.

Please scroll down to the end of the page for a full list.

 

 

Meeting Logistics

 

Registration

Each attendee must register (go to the Registration tab) and submit the title of their oral or poster presentation, if applicable. As with previous AID workshops, no registration fee will be charged. The organization committee will cover the costs of the meeting (including breakfasts, lunches, dinners, and conference costs). For the moment, the number of participants is limited to 96 due to logistics and places will be filled on a first-come-first-served basis. Once the limit of 96 registrants has been reached, a waiting list will be kept in case there are cancellations or that, funds permitting, we can accommodate additional participants.

 

Travel and accommodation

Attendees are responsible for booking and paying their own trip (go to the Travel tab for information) and accommodation (on- and off-site options are provided in the Accommodation tab). NOTE: If you need an invitation letter for obtaining a Visa, please communicate with one of the organizers.

 

Venue

Le Monastère des Augustines in Québec city, QC, Canada

The event will be held at a Quebec and Canadian landmark: a repurposed Monastery of the Augustinian Sisters, who arrived in Canada in 1639, founded 12 hospitals and laid the foundations of health care in Quebec. The Augustinian Monastery located in the old town in Quebec City was fully renovated in 2015 as a non-profit and now secular organization. Organizing this event at the Monastery, an award-winning location that brings together history and modern equipment helps support its social mission that includes programs for caregivers and low-cost accommodation for those accompanying patients at the Hôtel-Dieu hospital next door.

 

Quebec City is one of North America’s oldest and most charming cities. It was established in the 1500s and is the only fortified city in Canada and the United States. It is a UNESCO heritage site.

 

The meeting will coincide with Les Fêtes de la Nouvelle France which is held Thursday to Sunday, August 6-9, 2020. This festival celebrates the arrival of the first Europeans on American soil. The festivities include music shows, parades, and street entertainment.

 

 

 

 

 

 

 

The organizers would like to thank Alexandra Gervais from the IRCM, as well as Pierre Dupont and the IRCM Administration for their assistance with the organization.

August 4-6 2020

Monastère des Augustines
77 Rue des Remparts
Québec, Québec
Canada, G1R 0C3

Registrations
November 28, 2019 00:00 EST to April 1, 2020 00:00 EDT
Contact organizers
javier.di.noia@ircm.qc.ca

Sponsors