Schedule:

 

We are pleased to announce the preliminary schedule of events for the 2020 meeting!

 

DAY 1 – June 10th, 2020      

1:00pm-2:15pm – Parallel Trainee Events  

CRX040 – Resume workshop with the Ottawa Science to Business Network

CRX240 – Discussions on Equity Diversity and Inclusion in Science

2:15pm-3:15pm A Panel on Careers Outside of Academia, Trainee event, CRX240

2:15pm-3:15pm – NSERC Workshop for Discovery Grant Competition, CRX040

3:15pm-4:15pm Strategies for Science Communication, Trainee Event, CRX240

4:15pm- 5:15pm – Trainee Networking Social, CRX C300B   

5:15pm- 5:25pm – Opening Remarks

5:25pm-5:55pm – Jeanne Manery Fisher Memorial Lectureship, CRX240

5:55pm-6:10 pm – Special Presentation – WMISCAN Canada, CRX240

6:10pm-7:10pm – Keynote lecture – Markus Ralser - The Francis Crick Institute, CRX240   

7:10pm – Welcome Reception, C300B

 

DAY 2 – June 11th, 2020      

8:30am-9:45am – Parallel Platform Sessions

CRX140 – Cancer & Genome stability

CRX240 – Cardiac Signalling

9:45am-10:05am – Coffee Break, CRX C300B

10:05am-11:20am – Parallel Platform Sessions

CRX140 – Metabolic Engineering

CRX240 – Diabetes Signalling

11:20am-11:45am – Tech Talk, Presented by NanoString, CRX240

11:45am-1pm – Lunch, University Centre

1:00pm-1:30pm – CSMB New Investigator Award, CRX240

1:30pm-1:50pmArthur Wynne Gold Medal, CRX240

1:50pm-2:10pm – Coffee Break, CRX C300B

2:10-3:25pm – Parallel Platform Session

CRX140 – PTMs and Proteins

CRX240 – Kidney Signalling

3:25-5:15pm – Poster Session 1, CRX C300B

5:30-6:30pm – Dinner, University Centre

6:30pm-7:45pm – Parallel Platform Sessions

CRX140 – Mitochondrial Signalling

CRX240 – Immunometabolism

8:00pm-11:30pm – Trainee Pub Night 

 

DAY 3 – June 12th, 2020

8:30-9:45am – Parallel Platform Sessions

CRX140 – Lipid Signalling

CRX240 – Bioinformatics of Metabolic Networks

9:45am-10:05am – Coffee Break, CRX C300B           

10:05am-11:20am – Parallel Platform Sessions

CRX140 – Emerging Trends & New Technology

CRX240 – Bacterial & Viral Signalling

11:20am-12:00 pm – Canadian Science Publishing Senior Investigator Award, CRX240

12:00pm-1:00pm – Lunch, University Centre  

1:00pm-3:00pm – Annual General Meeting, CRX240  

3:00pm-4:15pm – Special Joint Session, CRX240, Rare Diseases

4:15pm-6:00pm – Poster Session 2, CRX C300B

6:30pm – Banquet at the National Arts Centre

 

DAY 3 – June 13th, 2020

Depart – See you next year!

 

Keynote Speaker: 

 

Markus Ralser, The Francis Crick Institute and University of Cambridge

 

Dr. Rasler is an expert in systems biology of metabolism. His research team uses the yeast model system to understand how individual metabolic pathways change and adapt as a collective in response to stress. His group uses a combination of techniques include mass spectrometry to investigate rapid perturbations to cell homeostasis. His work has implications for diverse diseases including cancer, diabetes and neurological disorders. In 2016, Dr. Ralser was awarded the Biochemical Society's Colworth Medal for his work in the area of cellular metabolism.

 

Keywords: Systems biology, metabolism, model systems, mass spectrometry

 

 

 

Scientific Sessions:

 

Kidney Signalling - Chair: Dr. Erin Mulvihill, Ottawa Heart Institute

Invited Speaker: Dr. Lisa Robinson, SickKids Toronto  

Dr. Robinson is a clinician-scientist whose lab studies the molecular mechanisms and cues including endothelial-expressed chemokines and sex hormones that guide the migration and differentiation of a number of bone marrow derived cell types in a number of conditions including inflammation, bone formation and kidney disease. She utilizes a number of genetic and pharmacologic approaches at both the cellular and whole organism level. She also has an active clinical research program based on the improving the care of renal transplant recipients, patients with immune-mediated kidney disease and children with kidney disease.

 

 Keywords: osteoclasts, sex hormones, kidney disease, leukocytes, inflammation

 

 

 

Bacterial and viral signalling - Chair: Dr. Salim Timo Islam, INRS

Invited Speaker: Dr. Yves Brun, Université de Montréal

 

Dr. Brun is a recent recruit from Indiana University at Bloomington under the Canada 150 Chairs Program. His lab studies diverse questions related to the life and times of bacteria with a focus on Caulobacter as a model system. His work in Montreal will continue his award-winning NIH-funded work begun at Indiana University. Join us in Welcoming Dr. Brun to Canada!

 

Key words: Caulobacter, peptidoglycan, morphogenesis, biofilms, bacterial ageing

 

 

 

 

 

 

PTMs & Proteins - Chair: Dr. Mike Downey, uOttawa

Invited Speaker: Dr. Claire Eyers, University of Liverpool

 

Dr. Claire Eyers is a full professor at the University of Liverpool, UK. Her group focuses on the development of new mass spectrometry approaches to study non-canonical signaling pathways and protein-protein interactions. Some of her recent define a wide scope for non-canonical phosphorylation on amino acids such as lysine, arginine and histidine in eukaryotic cells.

 

Key words: Analytical chemistry, phosphorylation, cell signaling, cool PTMs

 

 

 

 

 

Heart Signalling - Chair: Han Kim, Ottawa Heart Institute

Invited Speaker: Dr. Jason Dyck, University of Alberta

 

 

Dr. Dyck is the Director of the Cardiovascular Research Group at the University of Alberta. His research team is interested in links between cell signaling and cardiac energy metabolism. Ultimately his work is important for understanding cardiac diseases such as ischemia/reperfusion injury, arrhythmias, and cardiac hypertrophy.

 

Key words: cardiac biology, resveratrol, glucose, lipid signalling

 

 

 

 

 

Rare Diseases - Chair: Dr. Barbara Karten, Dalhousie University

Invited Speaker: Dr. Emily Eden, University College London

 

 

Dr. Eden is a senior Research Fellow at the Institute of Ophthalmology, Faculty of Brain Sciences at UCL. She studies the trafficking between the ER and lysosome and how defects in this process can lead to disease. Her group is particularly interested in the transport of lipids, such as cholesterol. Her work is critical for our understanding of rare diseases such as Niemann Pick type-C.                   

 

Key words: Niemann Pick type-C (NPC), lysosomal disorders, lipids, ER-lysosome trafficking

 

 

 

 

Mitochondrial biology - Chair: Dr. Mary-Ellen Harper, University of Ottawa

Invited Speaker: Dr. Rita Horvath, University of Cambridge

 

Dr. Horvath is a clinician-scientist dedicated to improving the understanding of genetic neurological conditions, with a strong focus on mitochondrial disease and inherited neuropathy. Her laboratory explores specific mitochondrial translation deficiencies as disease mechanisms and works to develop treatments for patients with mitochondrial disease and Charcot-Marie-Tooth disease. She uses several complementary approaches and methodologies, including RNA seq, whole-exome sequencing studies and proteomics.

 

Keywords: mitochondrial disease, genetics, metabolite transport; metabolomics; mitochondrial respiratory chain

 

 

 

Diabetes - Chair: Dr. Jennifer Estall, IRCM

Invited Speaker: Tim Kieffer, University of British Columbia

 

The Kieffer lab studies how hormones regulate blood glucose levels and aims to develop gene and cell therapy approaches to re-establish automatic release of insulin within patients with diabetes. Their approaches utilize model cell lines, differentiated stem cells, zebrafish and genetically engineered rodents. He is also working to translate his findings through a number of industry collaborations.

 

Keywords: stem cells, islets, beta cell regeneration, insulin, hormones, glycemia, encapsulation

 

 

 

 

 

Bioinformatics - Chair: Dr. Mathieu Lavallée-Adam, University of Ottawa

Invited Speaker: Dr. Jianguo (Jeff) Xia, McGill

 

Dr. Xia is an Assistant Professor at McGill University since 2015. His research explores theoretical and practical ways to address the critical challenges in big data analytics arising from biomedical research with the aim of developing highly innovative and useful approaches for metabolomics, transcriptomics, microbiomics and multi-omics integration. Dr. Xia has won several prestigious awards including a Canada Research Chair (Tier 2) and the McGill 2019 Principal’s Prize for Outstanding Emerging Researchers.

 

Keywords: Big Data, Bioinformatics, Metabolomics, Microbiomics

 

 

 

Cancer metabolism - Chair: Dr. Savraj Grewal, University of Calgary

Invited Speaker: Dr. Heidi Lempradl, Van Andel Research Institute

 

Dr. Lempradl is an Assistant professor at the Van Andel Research Institute (Grand Rapids Michigan, USA). Her team uses the power of the Drosophila model system to understand how changes in metabolic signalling pathways can impact cell function. Her unique work focuses on the impact of these pathways across generations, from parents to offspring.

 

Key words:  Obesity, diabetes, epigenetics, chromatin, transcription

 

 

 

 

Metabolic Engineering - Chair: Dr. Vincent Martin (Concordia University)

Invited Speaker: Radhakrishnan Mahadevan, University of Toronto

 

Dr. Mahadevan is a professor in the Chemical Engineering and Apply Chemistry Department at the University of Toronto. He studies how microorganisms can be used and manipulated to produce new sources of fuels and small molecules. His group is at the forefront of developing new technologies to re-program bacterial cells for new functions. Dr. Mahadevan is the winner of the 2017 Biochemical Engineering Journal Young Investigator Award.

 

Keywords: Metabolic engineering, chemistry, synthetic biology, bacteria, microbiome, DNA editing

 

 

 

 

 

Immunometabolism - Chair: Dr. Erin Mulvihill, Ottawa Heart Institute

Invited Speaker: Dr. Sue Tsai, University of Alberta

 

Dr. Tsai is a new investigator at the University of Alberta studying immunology and immunometabolism. Her lab is focused on understanding the regulation of the immune response and its connection to metabolism during chronic diseases such as Type 1 Diabetes (T1D) and Type 2 Diabetes (T2D). Using a combination of animal models and vaccination methodologies, her laboratory studies the role of immune and metabolic signaling in disease development and progression.

 

Keywords: Immunometabolism, immune tolerance, adaptive immunity, diabetes

 

 

 

 

Lipid Signalling - Chair: Dr. Vanina Zaremberg, University of Calgary

Invited Speaker: Toon de Kroon, Utrecht University

 

Dr. de Kroon is a professor at Utrecht University in the Netherlands. His research team studies biophysical properties of membranes and how this impacts the function of membrane proteins in the budding yeast. S. cerevisiae model system. His lab uses a combination of genetic and biochemical assays. In application-oriented research, he is also interested in how yeast can be modified to bioengineer hydrophobic molecules with specific properties.

 

Keywords: Lipids, bioengineering, biophysics, cell membranes, S. cerevisiae

 

 

 

 

Emerging trends in metabolism - Chair: Dr. Julie St. Pierre, University of Ottawa

Invited Speaker: Dr. Lawrence Kazak, McGill University

 

Dr. Lawrence Kazak is a new Assistant professor in the Biochemistry Department at McGill. University. His group uses a combination of mouse genetics, mass spectrometry and cell biology techniques to study thermogenesis in adipocytes and other aspects of mitochondrial energetics in cancer cells.  He has recently secured funding from CIHR, NSERC and CFI. Recent high-profile publications include a study in Nature Metabolism.

 

Keywords:  adipocytes, mitochondria, creatine, cancer, thermogenesis, cancer biology