Program Overview
Saturday, November 9, 2019
12:00 – 1:30 pm Welcome Lunch
1:30 – 1:45 pm Opening Remarks (Alan Cohen, Tamàs Fülöp, Pierrette Gaudreau, and William Fraser)
1:45 – 3:00 pm Session 1: Comparative Biology of Aging
1:45 - 2:10 pm Jean-François Lemaitre
Sex differences in lifespan and ageing: what can we learn from comparative studies?
2:10 - 2:35 pm Anne Bronikowski
Insights into mechanisms of aging from comparative studies of reptiles
2:35 - 3:00 pm Vera Gorbunova
Mechanisms of longevity in long-lived mammals
3:00 – 3:30 pm Coffee Break
3:30 – 4:45 pm Session 2: Nutrition and Aging
3:30 - 3:55 pm José A. Morais
Leucine is not required in conjunction with resistance training and optimized protein intake to reverse frailty
3:55 - 4:20 pm Alistair Senior
Dietary Macronutrients, Age-Specific Mortality and Variation in Age at Death
4:20 - 4:45 pm Philipp Gut
Targeted Nutrition for Disease Management
4:45 – 6:00 pm Session 3: Mechanisms of Biological Aging
4:45 - 5:10 pm Jacek Witkowski
Proteodynamics and aging of cells and organisms
5:10 - 5:35 pm Pierrette Gaudreau
Metabolomic and lipidomic signatures of MetS in older adults of the NuAge cohort
5:35 - 6:00 pm Ganghui Liu
Programming and reprogramming of aging
6:00 – 7:00 pm Debate: Do we know what aging is?
Pro: Brian Kennedy
Con: Alan Cohen
7:00 – 8:00 pm Dinner/Cocktail (Z Tapas Lounge, Hotel Restaurant)
8:00 – 8:45 pm Keynote 1: Claudio Franceschi
Causes and implications of the heterogeneity of the aging phenotype
Sunday, November 10, 2019
7:30 – 8:15 am Breakfast (for hotel guests)
8:15 – 9:30 am Session 4: Aging, Frailty, and Complexity
8:15 - 8:40 am Andrea Maier
Determinants of recovery from acute disease at older age: the RESORT cohort
8:40 - 9:05 am Marcel G. M. Olde Rikkert
Getting Grip on Resilience in Aging Adults
9:05 - 9:30 am Arnold Mitnitski
Systems approach to aging and frailty
9:30 – 10:45 am Coffee Break and Posters
10:45 am – 12:00 pm Session 5: Big Data, Artiticial Intelligence, and Aging
10:45 - 11:10 am Quentin Vanhaelen
Transforming aging research and drug discovery with multimodal AI-based integrated approaches
11:10 - 11:35 am Serafim Rodrigues and Mathieu Desroches
Can Topology-Structure-Function relationship help understand ageing?
11:35 am - 12:00 pm Johannes Hertel
Frameworks of constructing metrics of biological age via data-driven procedures
12:00 – 12:50 pm Keynote 2: Luigi Ferrucci
Paving the road to new generation of studies of aging: the GESTALT study
12:50 – 2:00 pm Lunch
2:00 – 3:20 pm Session 6: Immunosenescence and Inflammaging
2:00 - 2:20 pm Graham Pawelec
Impact of immunosenescence on cancer immunotherapy
2:20 - 2:40 pm Julian Falutz
Aging with HIV: is it accelerated, accentuated, or just complicated?
2:40 - 3:00 pm Janko Nicolich-Zugich
Aging of lymph nodes sets a critical stage for age-related immune dysfunction
3:00 - 3:20 pm Daniela Frasca
Obesity and B cell immunosenescence
3:20 – 3:50 pm Coffee Break
3:50 – 5:05 pm Session 7: Cellular Senescence
3:50 - 4:15 pm Bertrand Friguet
Proteome oxidative modifications and impairment of metabolic pathways during cellular senescence and aging
4:15 - 4:40 pm Gerardo Ferbeyre
Senescence, aging and the nucleolus
4:40 - 5:05 pm Stathis Gonos
Proteasome activation delays aging and the progression of age-related diseases
5:05 – 6:35 pm Session 8: Geroscience
5:05 - 5:30 pm Brian Kennedy
Small molecule approaches to slow aging in humans
5:30 - 5:55 pm Vadim N. Gladyshev
From longevity signatures to longevity interventions
5:55 - 6:20 pm Alexey Moskalev
Transcriptomic changes in long-living strains of Drosophila melanogaster
6:20 - 6:35 pm Jeremy van Raamsdonk
Molecular pathways that contribute to longevity as novel therapeutic targets for neurodegenerative disease
7:00 pm Speaker dinner (Z Tapas Lounge, Hotel Restaurant)
Monday, November 11, 2019
7:30 – 8:15 am Breakfast (for hotel guests)
8:15 – 9:00 am Keynote 3: Dominique Gravel
Aging in multiple dimensions
9:00 – 10:15 am Session 9: Systems Biology of Aging
9:00 - 9:25 am Jackie Jing-dong Han
Heterogeneity of aging in human populations
9:25 - 9:50 am Steve Horvath
Comparative epigenetic aging studies in mammals
9:50 - 10:15 am Anatoliy Yashin
Genetic connection among aging, health, and longevity related traits: The results of recent analyses
10:15 – 10:45 am Coffee Break
10:45 am – 12:00 pm Session 10: Age-Related Diseases
10:45 - 11:10 am Andrei Seluanov
The role of transposable elements in inflammaging
11:10 - 11:35 am Andreas Simm
Advanced Glycation Endproducts and Nutrition: Friend or foe during aging?
11:35 am - 12:00 pm André Carpentier
Adipose tissue metabolic dysfunction in cardiometabolic diseases
12:00 – 1:00 pm Lunch
1:00 – 2:15 pm Session 11: Longitudinal Studies
1:00 - 1:25 pm Parminder Raina
Integrating population aging and biology using CLSA as a platform
1:25 - 1:50 pm Joris Deelen
The genetic and metabolomic signatures of human longevity and lifespan
1:50 - 2:15 pm Anis Larbi
T cell aging in aging
2:15 – 2:45 pm Coffee Break
2:45 – 4:00 pm Session 12: Complexity and Aging
2:45 - 3:10 pm Svetlana Ukraintseva
Mechanisms of the decline in resilience during aging: Role of genes regulating cell responses to damage
3:10 - 3:35 pm Adam Freund
Untangling Aging Using Dynamic, Organism-Level Phenotypic Networks
3:35 - 4:00 pm Janet Thornton
Computational approaches to unravel the complexities of Ageing and repurpose drugs for geroprotection
4:00 – 5:15 pm Session 13: Interventions
4:00 - 4:25 pm Stephen Cunnane
Brain energy rescue with ketones in Alzheimer’s disease: progress with clinical trials
4:25 - 4:50 pm Katsuiku Hirokawa
Immune status of cancer patients and the effect of DC therapy with WT-1 peptide on immunity and prognosis
4:50 - 5:15 pm Jing Qu
Gene therapy alleviates osteoarthritis by preventing stem cell senescence